HPV is a non-enveloped, double-stranded DNA virus with a T = 7 icosahedral capsid composed of 72 L1 pentamers (capsomeres), which are paired with L2 monomers. The L1 and L2 proteins have similar molecular weights (approximately 55kDa), with minor differences among different HPV genotypes. HPV has evolved a highly refined infection mechanism and exhibits specificity regarding the…